Epilepsy research · 2026
Prognosis of feeding and swallowing function in children and adolescents/young adults after corpus callosotomy.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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История · было → стало
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Ishioka Risako, Yamakawa Kohei, Matsubara Kohei, Yamada Naoki, Fukuoka Masataka, Nukui Megumi, Inoue Takeshi, Kuki Ichiro, Ishimoto Kotaro, Umaba Ryoko, Kunihiro Noritsugu, Uda Takehiro, Okazaki Shin
Аннотация
BACKGROUND: Acute disconnection syndromes frequently occur after corpus callosotomy (CC), with poor oral intake being among the symptoms. Most patients achieve normal oral intake by 2 weeks postoperatively. However, in some cases, feeding and swallowing functions fail to recover, and risk factors for delayed improvement in oral intake remain unclear. This study aimed to investigate the frequency of delayed improvement in oral intake at 2 weeks after CC, to descriptively examine feeding and swallowing function outcomes at 6 months postoperatively, and to identify associated risk factors.
METHODS: A total of 76 CC procedures performed for refractory epilepsy between January 2015 and September 2023 were evaluated. Improvement in oral intake was classified as early (return to the usual form and quantity by postoperative week 2) or delayed (no improvement by week 2). Associations between clinical characteristics and delayed improvement in oral intake were analyzed.
RESULTS: Of the 76 procedures, 13 (17%) were classified into the delayed improvement group, and oral intake failed to return to the usual form and quantity for more than 6 months in 3 procedures, all of which required gastrostomy. In multivariate analysis, preoperative oral intake not being age-appropriate and older age at CC were independent risk factors.
CONCLUSIONS: Preoperative oral intake not being age-appropriate and older age at surgery are risk factors for delayed improvement in oral intake after CC. In patients with these risk factors, the possibility of delayed recovery should be considered and explained before surgery.
METHODS: A total of 76 CC procedures performed for refractory epilepsy between January 2015 and September 2023 were evaluated. Improvement in oral intake was classified as early (return to the usual form and quantity by postoperative week 2) or delayed (no improvement by week 2). Associations between clinical characteristics and delayed improvement in oral intake were analyzed.
RESULTS: Of the 76 procedures, 13 (17%) were classified into the delayed improvement group, and oral intake failed to return to the usual form and quantity for more than 6 months in 3 procedures, all of which required gastrostomy. In multivariate analysis, preoperative oral intake not being age-appropriate and older age at CC were independent risk factors.
CONCLUSIONS: Preoperative oral intake not being age-appropriate and older age at surgery are risk factors for delayed improvement in oral intake after CC. In patients with these risk factors, the possibility of delayed recovery should be considered and explained before surgery.