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DOI 10.1093/gerona/glab183

Медицинская библиотека · The journals of gerontology. Series A, Biological sciences and medical sciences · 2021

What Cut-Point in Gait Speed Best Discriminates Community-Dwelling Older Adults With Mobility Complaints From Those Without? A Pooled Analysis From the Sarcopenia Definitions and Outcomes Consortium.

Cawthon Peggy M, Patel Sheena M, Kritchevsky Stephen B, Newman Anne B, Santanasto Adam, Kiel Douglas P, Travison Thomas G, Lane Nancy, Cummings Steven R, Orwoll Eric S, Duchowny Kate A, Kwok Timothy, Hirani Vasant, Schousboe John, Karlsson Magnus K, Mellström Dan, Ohlsson Claes, Ljunggren Östen, Xue Qian-Li, Shardell Michelle, Jordan Joanne M, Pencina Karol M, Fielding Roger A, Magaziner Jay, Correa-de-Araujo Rosaly, Bhasin Shalender, Manini Todd M

СтатьяПоддержка NIH: внешняя программаПоддержка исследования: вне правительства СШАПоддержка службы здравоохранения СШАПеревод в очереди

Аннотация

BACKGROUND

Cut-points to define slow walking speed have largely been derived from expert opinion.

METHODS

Study participants (13 589 men and 5043 women aged ≥65years) had walking speed (m/s) measured over 4-6 m (mean ± SD: 1.20 ± 0.27 m/s in men and 0.94 ± 0.24 m/s in women.) Mobility limitation was defined as any self-reported difficulty with walking approximately 1/4 mile (prevalence: 12.6% men, 26.4% women). Sex-stratified classification and regression tree (CART) models with 10-fold cross-validation identified walking speed cut-points that optimally discriminated those who reported mobility limitation from those who did not.

RESULTS

Among 5043 women, CART analysis identified 2 cut-points, classifying 4144 (82.2%) with walking speed ≥0.75 m/s, which we labeled as "fast"; 478 (9.5%) as "intermediate" (walking speed ≥0.62 m/s but <0.75 m/s); and 421 (8.3%) as "slow" (walking speed <0.62 m/s). Among 13 589 men, CART analysis identified 3 cut-points, classifying 10 001 (73.6%) with walking speed ≥1.00 m/s ("very fast"); 2901 (21.3%) as "fast" (walking speed ≥0.74 m/s but <1.00 m/s); 497 (3.7%) as "intermediate" (walking speed ≥0.57 m/s but <0.74 m/s); and 190 (1.4%) as "slow" (walking speed <0.57 m/s). Prevalence of self-reported mobility limitation was lowest in the "fast" or "very fast" (11% for men and 19% for women) and highest in the "slow" (60.5% in men and 71.0% in women). Rounding the 2 slower cut-points to 0.60 m/s and 0.75 m/s reclassified very few participants.

CONCLUSIONS

Cut-points in walking speed of approximately 0.60 m/s and 0.75 m/s discriminate those with self-reported mobility limitation from those without.

Для цитирования: Cawthon Peggy M, Patel Sheena M, Kritchevsky Stephen B, Newman Anne B, Santanasto Adam, Kiel Douglas P, Travison Thomas G, Lane Nancy, Cummings Steven R, Orwoll Eric S, Duchowny Kate A, Kwok Timothy, Hirani Vasant, Schousboe John, Karlsson Magnus K, Mellström Dan, Ohlsson Claes, Ljunggren Östen, Xue Qian-Li, Shardell Michelle, Jordan Joanne M, Pencina Karol M, Fielding Roger A, Magaziner Jay, Correa-de-Araujo Rosaly, Bhasin Shalender, Manini Todd M. What Cut-Point in Gait Speed Best Discriminates Community-Dwelling Older Adults With Mobility Complaints From Those Without? A Pooled Analysis From the Sarcopenia Definitions and Outcomes Consortium.. The journals of gerontology. Series A, Biological sciences and medical sciences. 2021. DOI: 10.1093/gerona/glab183.

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