Congenital ocular motor apraxia with autosomal dominant inheritance.

PURPOSE: To document congenital ocular motor apraxia in five first-degree relatives.

METHODS

Case series. Five family members with a history of horizontal head thrusting had neuro-ophthalmologic evaluation. Magnetic resonance imaging of the brain was obtained in the proband.

RESULTS

Four siblings (one boy and three girls) had congenital ocular motor apraxia. The father had head thrusting as a child and displayed residual signs of the disorder. Magnetic resonance imaging disclosed no central nervous system abnormalities in the father.

CONCLUSION

Congenital ocular motor apraxia can be inherited as an autosomal dominant trait.