MedElevator Войти в исследования
← Поиск публикаций

DOI 10.1186/s12917-019-1946-1

Медицинская библиотека · BMC veterinary research · 2019

Pedobarography: a novel approach to test the efficacy of treatments for lameness; an experience with mavacoxib in dogs with elbow osteoarthritis.

López Sergio, Vilar José M, Rubio Mónica, Sopena Joaquín J, Santana Angelo, Rodríguez Oliver, Rodríguez-Altonaga José A, Carrillo José M

СтатьяПеревод в очереди

Аннотация

BACKGROUND

Pedobarographic analyses detect pressure redistribution among limbs and within limbs in humans, equids and dogs. The main objective of this study was to assess the usefulness of a set of pedobarographic parameters for the detection of lameness, as well as for its suitability for assessing the effects of therapies against osteoarthritis in dogs. With this purpose, eleven large-breed lame dogs with unilateral osteoarthritis due to elbow dysplasia were evaluated using a pressure platform prior to (D0) and after 3 months (D90) of treatment with mavacoxib, a COX-2 selective NSAID. The obtained parameters were: pressure distribution between lame and sound limbs, as well as paw area, mean pressure, and peak pressure of both lame and sound limbs.

RESULTS

The results showed statistical differences in all these parameters between lame and sound limbs at D0; however, at D90, differences were significantly decreased as result of the treatment, indicating a substantial functional recovery under the study design conditions.

CONCLUSIONS

The provided data prove the suitability of this novel technique in canine models for the quantitative and objective assessment of lameness, but also for the evaluation of treatments for lameness caused by articular pain.

Для цитирования: López Sergio, Vilar José M, Rubio Mónica, Sopena Joaquín J, Santana Angelo, Rodríguez Oliver, Rodríguez-Altonaga José A, Carrillo José M. Pedobarography: a novel approach to test the efficacy of treatments for lameness; an experience with mavacoxib in dogs with elbow osteoarthritis.. BMC veterinary research. 2019. DOI: 10.1186/s12917-019-1946-1.

Предметные рубрики MeSH

Подготовка и перевод публикации
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…

История · было → стало

Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.

Тип публикации указан по данным источника. Уровень доказательности автоматически не присваивается.