Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit · 2006
Seroprevalence of hepatitis C virus specific antibodies among Iraqi children with thalassaemia.
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Al-Kubaisy W A, Al-Naib K T, Habib M
Аннотация
The seroprevalence of hepatitis C virus (HCV) specific antibodies and HCV genotypes distribution were studied among 559 Iraqi children with thalassaemia in receipt of repeated blood transfusions. HCV-specific antibodies were detected in 376 (67.3%) serum samples using third-generation enzyme immunoassay and confirmatory immunoblot assays. Of 78 randomly selected sera, 48 (61.5%) were HCV-RNA positive. HCV genotypes 1a, 1b, 4 and mixed 1b and 4 were demonstrated in 13 (27.1%), 11 (22.9%), 17 (35.4%) and 7 (14.6%) sera respectively. Strict measures for the controlling the spread of HCV are needed by introducing advanced techniques for blood donor screening.
Предметные рубрики MeSH
Blood DonorsChildChild WelfareChild, PreschoolComorbidityCross-Sectional StudiesDonor SelectionGenotypeHepacivirusHepatitis CHepatitis C AntibodiesHospitals, TeachingHumansImmunoblottingImmunoenzyme TechniquesInfection ControlIraqPopulation SurveillanceRNA, ViralReverse Transcriptase Polymerase Chain ReactionSeroepidemiologic StudiesThalassemiaTransfusion ReactionUrban Health