International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2026
First successful treatment of phaeohyphomycosis due to Medicopsis romeroi with isavuconazole in a renal transplant recipient in France.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Machouart Marie, Cottrel Claire, Karray Rahma, Hénard Sandrine, Melone Agnes, Debourgogne Anne
Аннотация
OBJECTIVES: We report a case of Medicopsis romeroi phaeohyphomycosis in a 25-year-old Malian patient residing in France for 4 years. He developed lesions on his right foot 6 months after receiving immunosuppressive therapy for a renal transplant.
METHODES: Microscopic examination of the biopsy revealed septate hyphae, and the culture grew a black mold without fructification, thereby enabling identification. The diagnosis was made with molecular tools, and therapy was initiated with isavuconazole.
RESULTS: This case is the first reported successful use of isavuconazole for this pathogen.
CONCLUSION: Clinicians and biologists should be aware of the risk of infection with dematiaceous fungi in solid organ transplant patients from tropical areas.
METHODES: Microscopic examination of the biopsy revealed septate hyphae, and the culture grew a black mold without fructification, thereby enabling identification. The diagnosis was made with molecular tools, and therapy was initiated with isavuconazole.
RESULTS: This case is the first reported successful use of isavuconazole for this pathogen.
CONCLUSION: Clinicians and biologists should be aware of the risk of infection with dematiaceous fungi in solid organ transplant patients from tropical areas.