Evaluation of toxic activity of 2,4-dihydroxythiobenzanilides.

2,4-Dihydroxythiobenzanilides represent a new group of compounds with significant fungistatic and bacteriostatic properties. The results of investigations on their cytotoxicity are also very convincing. Therefore LD50 doses were determined for five compounds, they ranged from 239 to 840.5 mg/kg. The results of the tests for spontaneous locomotor activity and hexabarbiturane sleeping time indicate low toxicity of the compounds tested.