Acta oto-laryngologica · 2010
Endolymphatic hydrops revealed by intravenous gadolinium injection in patients with Ménière's disease.
Клинический случайСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Nakashima Tsutomu, Naganawa Shinji, Teranishi Masaaki, Tagaya Mitsuhiko, Nakata Seiichi, Sone Michihiko, Otake Hironao, Kato Ken, Iwata Tomoyuki, Nishio Naoki
Аннотация
CONCLUSION: Visualization of endolymphatic hydrops became possible after intravenous gadolinium (Gd) injection in patients with Ménière's disease.
OBJECTIVE: To visualize endolymphatic hydrops after intravenous Gd injection.
METHODS: Gd (gadoteridol; 0.2 mmol/kg) was injected intravenously in three patients with unilateral Ménière's disease. We performed three-dimensional fluid attenuated inversion recovery (3D-FLAIR) and three-dimensional real inversion recovery (3D-real IR) magnetic resonance imaging (MRI) 4 h after the injection using a 3-Tesla MRI unit. We used a 32-channel array coil to obtain a high signal-to-noise ratio.
RESULTS: Endolymphatic hydrops was observed in the ears of patients with Ménière's disease. However, Gd concentration in the perilymph was lower compared with that obtained after intratympanic Gd injection.
OBJECTIVE: To visualize endolymphatic hydrops after intravenous Gd injection.
METHODS: Gd (gadoteridol; 0.2 mmol/kg) was injected intravenously in three patients with unilateral Ménière's disease. We performed three-dimensional fluid attenuated inversion recovery (3D-FLAIR) and three-dimensional real inversion recovery (3D-real IR) magnetic resonance imaging (MRI) 4 h after the injection using a 3-Tesla MRI unit. We used a 32-channel array coil to obtain a high signal-to-noise ratio.
RESULTS: Endolymphatic hydrops was observed in the ears of patients with Ménière's disease. However, Gd concentration in the perilymph was lower compared with that obtained after intratympanic Gd injection.
Предметные рубрики MeSH
AdultAgedCochleaContrast MediaEndolymphatic HydropsFemaleGadoliniumHearing Loss, SensorineuralHeterocyclic CompoundsHumansImage Processing, Computer-AssistedImaging, Three-DimensionalInjections, IntravenousMagnetic Resonance ImagingMaleMeniere DiseaseMiddle AgedNeuroma, AcousticOrganometallic CompoundsVestibule, Labyrinth