Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
The Canadian multi-ethnic research on aging (CAMERA) study: Design, participant characteristics, and preliminary findings.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Marawi Tulip, Rai Harleen, Kumar Rohina, Vandeloo Katie L, Yep Rachel, Alexander Madeline Wood, Boshmaf Silina Z, Chen Sarah-Mei, Gopinath Georgia, Malhotra Simran, Zhang Angelina, Nyman Alexander J, Perri Lucas Xavier, Sit Valery, Splinter Tallinn F L, Munoz Douglas P, Swardfager Walter, Ryan Jennifer D, Black Sandra E, Goubran Maged, Rabin Jennifer S
Аннотация
INTRODUCTION: South Asian and Chinese individuals are the largest and fastest-growing ethnoracial groups in Canada, yet they remain underrepresented in dementia research. To address this gap, we established the CAnadian Multi-Ethnic Research on Aging (CAMERA) study.
METHODS: CAMERA is a longitudinal observational study conducted in Toronto, Canada, enrolling 300 adults aged 55-85 who self-identify as South Asian, Chinese, or non-Hispanic White (NHW). Participants complete in-person visits at baseline, Year 3, and Year 5, which include clinical and cognitive assessments, brain magnetic resonance imaging (MRI), and blood-based biomarkers. Annual remote questionnaires track health and lifestyle factors.
RESULTS: Among the first 200 participants, vascular and metabolic profiles differed across groups. In addition, South Asian and Chinese participants reported greater cognitive concerns than NHW participants and had lower Montreal Cognitive Assessment (MoCA) scores. The latter was driven primarily by language-heavy and culturally dependent items. Eye-tracking measures did not differ across groups.
DISCUSSION: CAMERA provides a deep phenotyping framework to investigate dementia risk and resilience factors in Asian Canadians.
METHODS: CAMERA is a longitudinal observational study conducted in Toronto, Canada, enrolling 300 adults aged 55-85 who self-identify as South Asian, Chinese, or non-Hispanic White (NHW). Participants complete in-person visits at baseline, Year 3, and Year 5, which include clinical and cognitive assessments, brain magnetic resonance imaging (MRI), and blood-based biomarkers. Annual remote questionnaires track health and lifestyle factors.
RESULTS: Among the first 200 participants, vascular and metabolic profiles differed across groups. In addition, South Asian and Chinese participants reported greater cognitive concerns than NHW participants and had lower Montreal Cognitive Assessment (MoCA) scores. The latter was driven primarily by language-heavy and culturally dependent items. Eye-tracking measures did not differ across groups.
DISCUSSION: CAMERA provides a deep phenotyping framework to investigate dementia risk and resilience factors in Asian Canadians.