Research in developmental disabilities · 2025
The lower limb coordination, brain activation during walking and their correlation in adolescents with spastic cerebral palsy: A pilot cross-sectional fNIRS study.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Zhou Fenyan, Qi Liuxin, Sun Wei, Wang Jiangna
Аннотация
BACKGROUND: This study aimed to explore the lower limb coordination and brain activation in adolescents with cerebral palsy (CP) during walking, and to investigate their relationship.
METHODS: 8 adolescents with spastic CP were recruited as the CP group and 8 typically developing (TD) adolescents as the control group. Functional near-infrared spectroscopy (fNIRS) and the Vicon motion capture system were used to collect hemodynamic signals and kinematic data during walking, respectively.
RESULTS: The mean absolute value of the continuous relative phase (MACRP) values of hip-knee joint was lower but deviation phase (DP) values of hip-knee and knee-ankle joints was higher. The activation levels of the supplementary motor area (SMA), the pre-central gyrus (PRG), the post-central gyrus (POG), and the superior parietal lobe (SPL) were higher. The DP of hip-knee joint was positively correlated with the SPL (channels 9,18) and right POG (channel 17), whereas the DP of the knee-ankle joint was positively correlated with the right POG (channel 17). In the control group, the MACRP of knee-ankle joint was positively correlated with the right PRG and POG (channel 15). The DP of hip-knee joint was positively correlated with the right SMA (channel 12) but negatively correlated with the left SPL (channel 9).
CONCLUSION: Adolescents with CP exhibit a higher variability in hip-knee and knee-ankle joints in the coordination patterns and greater demand for activation of the sensorimotor cortex during walking. The over-activation of the parietal cortex may lead to increased variability in the coordination patterns of individuals with CP.
METHODS: 8 adolescents with spastic CP were recruited as the CP group and 8 typically developing (TD) adolescents as the control group. Functional near-infrared spectroscopy (fNIRS) and the Vicon motion capture system were used to collect hemodynamic signals and kinematic data during walking, respectively.
RESULTS: The mean absolute value of the continuous relative phase (MACRP) values of hip-knee joint was lower but deviation phase (DP) values of hip-knee and knee-ankle joints was higher. The activation levels of the supplementary motor area (SMA), the pre-central gyrus (PRG), the post-central gyrus (POG), and the superior parietal lobe (SPL) were higher. The DP of hip-knee joint was positively correlated with the SPL (channels 9,18) and right POG (channel 17), whereas the DP of the knee-ankle joint was positively correlated with the right POG (channel 17). In the control group, the MACRP of knee-ankle joint was positively correlated with the right PRG and POG (channel 15). The DP of hip-knee joint was positively correlated with the right SMA (channel 12) but negatively correlated with the left SPL (channel 9).
CONCLUSION: Adolescents with CP exhibit a higher variability in hip-knee and knee-ankle joints in the coordination patterns and greater demand for activation of the sensorimotor cortex during walking. The over-activation of the parietal cortex may lead to increased variability in the coordination patterns of individuals with CP.