Journal of clinical pathology · 2012
Complex adnexal tumours of the skin: a report of three cases and review of literature.
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London Vanessa, Saadat Payam, Vadmal Manjunath S
Аннотация
AIMS: Complex or composite adnexal tumours of the skin (CATS) are unusual neoplasms composed of two or more histopathologically distinct subtypes of appendageal neoplasms coexisting in a single cutaneous lesion. The authors report three examples of CATS, review literature and discuss their probable histogenesis.
METHODS AND RESULTS: Of the three tumours described, one tumour showed a mixture of a proliferating pilar tumour and syringocystadenoma papilliferum, the second lesion was composed of a proliferating pilar tumour and tubulopapillary hidradenoma and the third tumour exhibited a syringocystadenoma papilliferum and tubulopapillary hidradenoma in combination.
CONCLUSIONS: CATS are rare tumours. The authors reported three unique cases in addition to the 10 other reported cases. These three cases further strengthen the hypothesis of a 'folliculosebaceous apocrine' unit as the most likely point of origin of CATS.
METHODS AND RESULTS: Of the three tumours described, one tumour showed a mixture of a proliferating pilar tumour and syringocystadenoma papilliferum, the second lesion was composed of a proliferating pilar tumour and tubulopapillary hidradenoma and the third tumour exhibited a syringocystadenoma papilliferum and tubulopapillary hidradenoma in combination.
CONCLUSIONS: CATS are rare tumours. The authors reported three unique cases in addition to the 10 other reported cases. These three cases further strengthen the hypothesis of a 'folliculosebaceous apocrine' unit as the most likely point of origin of CATS.