Quality of life in children with defecation disorders compared with healthy.

To investigate the quality of life of children with defecation disorders by comparing with a healthy control group. A cross-sectional study enrolled children with defecation disorders from a tertiary hospital (June-July 2024) and age- and sex-frequency matched healthy controls from three communities (August 2024). Participants were recruited according to the inclusion and exclusion criteria. Quality of life was assessed using the Chinese version of the Pediatric Quality of Life Inventory™ 4.0, encompassing physical, emotional, social, and cognitive dimensions (scored 0-100). Caregiver-reported negative emotions in children with defecation disorders were also documented. Children with defecation disorders had significantly lower quality of life scores in physical health, emotional function, social function, and cognitive function (P < 0.001). Nearly half of caregivers reported negative emotions, with irritability, depression, and fatigue being most common. Children with defecation disorders have significantly lower quality of life than healthy children. Healthcare providers should address the comprehensive quality of life including psychological, emotional, and social integration aspects.