Pediatric pulmonology · 2026
Frequency, Demographic and Clinical Characteristics of Pediatric Lophomoniasis: A Cross-Sectional Study in Northern Iran.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Mazandarani Mahdi, Ahani Azari Raeen, Tajik Jalayeri Mohammad Hadi, Ghorbani Somayeh, Lashkarbolouk Narges, Shahkar Lobat
Аннотация
BACKGROUND: Lophomoniasis is an emerging respiratory infection, but its clinical and epidemiological characteristics in pediatric populations remain poorly defined. This study aimed to determine the prevalence and describe the clinical, radiological, and bronchoscopic features of lophomoniasis in children admitted to a pediatric respiratory referral center.
MATERIAL AND METHODS: A cross-sectional study was conducted at Taleghani Pediatric Hospital. The study enrolled 121 pediatric patients admitted with persistent respiratory symptoms and a clinical indication for bronchoscopy. Bronchoalveolar lavage (BAL) samples were used to diagnose lophomoniasis.
RESULTS: The frequency of lophomoniasis was 18.1% (22/121 patients). Mean age of lophomonas-positive patients was 8.03 years and they were primarily female (54.5%). Common presenting symptoms included cough (86.4%), fever (68.2%), and sputum (54.5%). Key findings included consolidation on radiography (54.5%), increased bronchial wall thickness on bronchoscopy (63.6%), and anemia (95.5%) in laboratory results. A significant majority (72.7%) had underlying diseases, most commonly cystic fibrosis (31.8%) and tuberculosis (13.6%). Statistical analysis revealed that lophomoniasis was significantly associated with the presence of any underlying disease (p = 0.001). Other significant associations were observed with positive CRP (p = 0.024), leukocytosis (p = 0.025), radiographic consolidation (p = 0.018), and the presence of a hydatid cyst (p = 0.041). Demographic factors such as age, gender, ethnicity, and place of residence were not significantly associated with the infection.
CONCLUSION: Lophomonasis is a frequent condition among children with chronic respiratory symptoms requiring bronchoscopy. Its strong association with underlying respiratory diseases highlights the need for systematic screening in this vulnerable population. Bronchoscopy with BAL is a valuable diagnostic tool, particularly when specific clinical and radiological findings are present.
MATERIAL AND METHODS: A cross-sectional study was conducted at Taleghani Pediatric Hospital. The study enrolled 121 pediatric patients admitted with persistent respiratory symptoms and a clinical indication for bronchoscopy. Bronchoalveolar lavage (BAL) samples were used to diagnose lophomoniasis.
RESULTS: The frequency of lophomoniasis was 18.1% (22/121 patients). Mean age of lophomonas-positive patients was 8.03 years and they were primarily female (54.5%). Common presenting symptoms included cough (86.4%), fever (68.2%), and sputum (54.5%). Key findings included consolidation on radiography (54.5%), increased bronchial wall thickness on bronchoscopy (63.6%), and anemia (95.5%) in laboratory results. A significant majority (72.7%) had underlying diseases, most commonly cystic fibrosis (31.8%) and tuberculosis (13.6%). Statistical analysis revealed that lophomoniasis was significantly associated with the presence of any underlying disease (p = 0.001). Other significant associations were observed with positive CRP (p = 0.024), leukocytosis (p = 0.025), radiographic consolidation (p = 0.018), and the presence of a hydatid cyst (p = 0.041). Demographic factors such as age, gender, ethnicity, and place of residence were not significantly associated with the infection.
CONCLUSION: Lophomonasis is a frequent condition among children with chronic respiratory symptoms requiring bronchoscopy. Its strong association with underlying respiratory diseases highlights the need for systematic screening in this vulnerable population. Bronchoscopy with BAL is a valuable diagnostic tool, particularly when specific clinical and radiological findings are present.