Cornea · 2007
Post-LASIK epithelial dendritic defect associated with Alternaria.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Kocatürk Tolga, Pineda Roberto, Green Laura K, Azar Dimitri T
Аннотация
PURPOSE: To report a case of a dendritic epithelial defect with interface inflammation associated with Alternaria sp. after laser in situ keratomileusis (LASIK) surgery.
METHODS: A case report of a 46-year-old woman who presented with a dendritic epithelial defect and interface inflammation after LASIK surgery.
RESULTS: After an apparent post-LASIK herpes simplex keratitis with related interface inflammation failed to respond to medical therapy, cornea culture results were positive for Alternaria fungal sp. 2 weeks and 6 days after presentation. Viral cultures and polymerase chain reaction were negative for herpes simplex virus. Six months after penetrating keratoplasty (and 1 year after LASIK), the patient underwent a cataract extraction OD. Best-corrected visual acuity 18 months after the original LASIK procedure was 20/25 OD.
CONCLUSIONS: Alternaria keratitis may present with a dendritic epithelial defect with interface inflammation mimicking herpes simplex virus.
METHODS: A case report of a 46-year-old woman who presented with a dendritic epithelial defect and interface inflammation after LASIK surgery.
RESULTS: After an apparent post-LASIK herpes simplex keratitis with related interface inflammation failed to respond to medical therapy, cornea culture results were positive for Alternaria fungal sp. 2 weeks and 6 days after presentation. Viral cultures and polymerase chain reaction were negative for herpes simplex virus. Six months after penetrating keratoplasty (and 1 year after LASIK), the patient underwent a cataract extraction OD. Best-corrected visual acuity 18 months after the original LASIK procedure was 20/25 OD.
CONCLUSIONS: Alternaria keratitis may present with a dendritic epithelial defect with interface inflammation mimicking herpes simplex virus.
Предметные рубрики MeSH
AlternariaAmphotericin BAntifungal AgentsCombined Modality TherapyCorneal UlcerDebridementDrug CombinationsDrug Therapy, CombinationEpithelium, CornealEye Infections, FungalFemaleHumansItraconazoleKeratomileusis, Laser In SituKeratoplasty, PenetratingMiddle AgedMycosesOfloxacinPolymyxin BPostoperative ComplicationsTrimethoprim