Gaceta medica de Mexico · 2025
Prevalence of suspected non-alcoholic fatty liver disease in pediatric patients.
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Méndez-Castro José de J, Méndez-Castro Juan M, Yudovich-Virsub Martin, Sosa-Farias Irvin A, Lezama-González Jacqueline, Méndez-Olivares Roberto, Serrano-Campos Flor A, Rugerio-Tellez Mónica, Ayón-Aguilar Jorge, García-Flores Máximo A, Méndez-Martínez Socorro
Аннотация
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) affects 9-18% of the general pediatric population, and 41-53% of obese children, with a higher risk in the Hispanic population.
OBJECTIVE: To determine the prevalence of suspected NAFLD in pediatric patients.
MATERIAL AND METHODS: A retrospective study of pediatric medical records, including anthropometric and biochemical data. Suspicion of NAFLD was assessed using body mass index (BMI) for age, the triglyceride-glucose (TyG) index, and the hepatic steatosis index (HSI).
RESULTS: 240 medical records were analyzed. The prevalence of suspected NAFLD based on BMI was 68.3%, using TyG was 62.5%, and using HSI, evaluated in 32 patients with complete laboratory data, was 31%. The age was of 14 years-old (11-16), with 59.6% female patients, weight 61 ± 17.4 kg, height 156.0 ± 11.7 cm, BMI 24.7 ± 5.4 kg/m², and BMI-for-age 92.6% (69.5-97.1%). 2.5% patients were underweighted, 34.2% had normal weight, 22.9% were overweight, 25.4% had obesity, and 15% had severe obesity.
CONCLUSIONS: The prevalence of overweight and obesity was 22.9% and 40.4%, respectively. The suspicion of NAFLD was higher than other cohorts.
OBJECTIVE: To determine the prevalence of suspected NAFLD in pediatric patients.
MATERIAL AND METHODS: A retrospective study of pediatric medical records, including anthropometric and biochemical data. Suspicion of NAFLD was assessed using body mass index (BMI) for age, the triglyceride-glucose (TyG) index, and the hepatic steatosis index (HSI).
RESULTS: 240 medical records were analyzed. The prevalence of suspected NAFLD based on BMI was 68.3%, using TyG was 62.5%, and using HSI, evaluated in 32 patients with complete laboratory data, was 31%. The age was of 14 years-old (11-16), with 59.6% female patients, weight 61 ± 17.4 kg, height 156.0 ± 11.7 cm, BMI 24.7 ± 5.4 kg/m², and BMI-for-age 92.6% (69.5-97.1%). 2.5% patients were underweighted, 34.2% had normal weight, 22.9% were overweight, 25.4% had obesity, and 15% had severe obesity.
CONCLUSIONS: The prevalence of overweight and obesity was 22.9% and 40.4%, respectively. The suspicion of NAFLD was higher than other cohorts.