[The 5-fluorouracil content of the pancreas and parapancreatic tissues when it is administered regionally into the tissue of the round ligament of the liver].

In the experiment on 31 dogs there was shown a significant increase of 5-fluorouracil concentrations in the pancreas and parapancreatic tissues with regional methods of its administration in the fat of the round ligament of the liver. A more prolonged preservation of the drug concentrations at the therapeutic level in the blood was observed. The most effective method of the cytostatic therapy is the regional lymphotropic method.