Nature neuroscience · 2015
Family income, parental education and brain structure in children and adolescents.
Сравнительное исследованиеСтатьяПоддержка NIH: внешняя программаПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Noble Kimberly G, Houston Suzanne M, Brito Natalie H, Bartsch Hauke, Kan Eric, Kuperman Joshua M, Akshoomoff Natacha, Amaral David G, Bloss Cinnamon S, Libiger Ondrej, Schork Nicholas J, Murray Sarah S, Casey B J, Chang Linda, Ernst Thomas M, Frazier Jean A, Gruen Jeffrey R, Kennedy David N, Van Zijl Peter, Mostofsky Stewart, Kaufmann Walter E, Kenet Tal, Dale Anders M, Jernigan Terry L, Sowell Elizabeth R
Аннотация
Socioeconomic disparities are associated with differences in cognitive development. The extent to which this translates to disparities in brain structure is unclear. We investigated relationships between socioeconomic factors and brain morphometry, independently of genetic ancestry, among a cohort of 1,099 typically developing individuals between 3 and 20 years of age. Income was logarithmically associated with brain surface area. Among children from lower income families, small differences in income were associated with relatively large differences in surface area, whereas, among children from higher income families, similar income increments were associated with smaller differences in surface area. These relationships were most prominent in regions supporting language, reading, executive functions and spatial skills; surface area mediated socioeconomic differences in certain neurocognitive abilities. These data imply that income relates most strongly to brain structure among the most disadvantaged children.