Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology · 2014
[Prevalence of H. pylori CagA strain and characteristics of associated gastritis in schoolchildren with dyspepsia syndrome in Tyva Republic].
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Polivanova T V, Vshivkov V A
Аннотация
AIM: To study the prevalence of H. pylori CagA strain and the activity of associated gastritis in schoolchildren of Tyva Republic (Russia).
MATERIALS AND METHODS: The cohorts had been formed out of 1064 native and alien schoolchildren picked up by random in Tyva Republic in the ages from 7 to 17 years. We determined IgG to H. pylori CagA antigen in serum (106 aliens and 112 natives). Out them 59 Tuvins and 72 Europoids with dyspeptic complaints were provided with endoscopic tests including biopsy of mucosa of antrum and stomach body.
RESULTS: We had found ethnic peculiarities in the obtained indices in children, namely higher prevalence of the said strain of H. pylori and the absence of meaningful activity in antral sector and body of stomach in CagA-seropositive native children as compared to alien ones, in whom the activity of antral gastritis was higher than the activity in body of stomach.
MATERIALS AND METHODS: The cohorts had been formed out of 1064 native and alien schoolchildren picked up by random in Tyva Republic in the ages from 7 to 17 years. We determined IgG to H. pylori CagA antigen in serum (106 aliens and 112 natives). Out them 59 Tuvins and 72 Europoids with dyspeptic complaints were provided with endoscopic tests including biopsy of mucosa of antrum and stomach body.
RESULTS: We had found ethnic peculiarities in the obtained indices in children, namely higher prevalence of the said strain of H. pylori and the absence of meaningful activity in antral sector and body of stomach in CagA-seropositive native children as compared to alien ones, in whom the activity of antral gastritis was higher than the activity in body of stomach.