Recent Advances in the Pathology of Pediatric Brain and Spinal Tumors.

The last decade has seen major advances in our understanding of the biology of pediatric brain and spinal cord tumors and why they are fundamentally different from their adult counterparts. Many of these advances have been adapted into the latest WHO classification of tumors of the central nervous system. This article summarizes the major changes to the WHO classification in this area, highlighting the key histopathologic and molecular features of these new entities.