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DOI 10.1007/s00062-025-01588-3

Медицинская библиотека · Clinical neuroradiology · 2025

A Child with Epileptic Seizure: A Case of Significantly Enhanced MVNT.

Fan Lei, Zhao Jianshe

СтатьяКлинический случайОбзорПеревод пока не подготовлен

Аннотация

OBJECTIVE

This case report aims to describe an unusual presentation of multinodular and vacuolating neuronal tumor (MVNT) in a pediatric patient, highlighting its atypical radiological and clinical features.

METHODS

We present the case of an 8-year-old boy with a 7-month history of seizures that progressed to daily episodes. Diagnostic workup included electroencephalography (EEG) and magnetic resonance imaging (MRI) with contrast. The lesion was resected surgically, and the diagnosis was confirmed histopathologically and immunohistochemically.

RESULTS

EEG revealed ictal discharges in the left central, parietal, and mid-posterior temporal regions. MRI showed a left frontal cortical lesion with T1 hypointensity, T2/FLAIR hyperintensity, and unusual marked contrast enhancement, mimicking ganglioglioma. Histopathological examination confirmed MVNT. Postoperatively, the patient experienced mild left limb weakness but remained seizure-free at one-month follow-up.

CONCLUSION

This case illustrates that MVNT can rarely occur in children and may exhibit prominent contrast enhancement and a ganglioglioma-like imaging appearance, posing a diagnostic challenge. Neurosurgeons and neuroradiologists should consider MVNT in the differential diagnosis of enhancing cortical lesions in pediatric epilepsy patients. Histopathological verification remains essential for definitive diagnosis.

Для цитирования: Fan Lei, Zhao Jianshe. A Child with Epileptic Seizure: A Case of Significantly Enhanced MVNT.. Clinical neuroradiology. 2025. DOI: 10.1007/s00062-025-01588-3.

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