Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
Epidemiology of nummular eczema - methodological approaches and outcomes from nationwide claims data analyses.
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Hagenström Kristina, Müller Katharina, Klinger Theresa, Willers Charlotte, Eyerich Kilian, Augustin Matthias
Аннотация
BACKGROUND AND OBJECTIVES: Nummular eczema (NE) is a chronic skin condition with limited epidemiologic data. This study estimates its prevalence, incidence and severity in Germany.
METHODS: A cross-sectional analysis (2016-2022) used German insurance claims data to identify NE cases (ICD-10 L30.0) and assess severity (hospitalization, work disability, systemic treatment) and comorbid skin conditions, including atopic dermatitis (AD).
RESULTS: In 2022, the prevalence of NE ranged from 0.07% to 0.26%. The incidence was 0.16%-0.17%. The mean age was 47.5 years, and 57.4% of the patients were male. Older males had a higher prevalence, while children younger than six years (0.34%), especially those younger than 2 years (0.56%-0.57%), were more affected. Severe NE was found in 14.8% of the patients. AD co-occurred in 18% of NE cases. NE patients had an increased risk of lichen simplex chronicus (RR 9.71), irritant contact dermatitis (RR 9.60), pruritus (RR 5.71), allergic rhinitis (RR 1.78), and allergic asthma (RR 1.49).
CONCLUSIONS: Despite differences in methodological approaches leading to some variation, the prevalence of NE in the German population can be reasonably estimated at approximately 0.26%. Overlaps and miscoding may have occurred, particularly with other forms of eczema, underscoring the need for reliable diagnostics and standardized coding.
METHODS: A cross-sectional analysis (2016-2022) used German insurance claims data to identify NE cases (ICD-10 L30.0) and assess severity (hospitalization, work disability, systemic treatment) and comorbid skin conditions, including atopic dermatitis (AD).
RESULTS: In 2022, the prevalence of NE ranged from 0.07% to 0.26%. The incidence was 0.16%-0.17%. The mean age was 47.5 years, and 57.4% of the patients were male. Older males had a higher prevalence, while children younger than six years (0.34%), especially those younger than 2 years (0.56%-0.57%), were more affected. Severe NE was found in 14.8% of the patients. AD co-occurred in 18% of NE cases. NE patients had an increased risk of lichen simplex chronicus (RR 9.71), irritant contact dermatitis (RR 9.60), pruritus (RR 5.71), allergic rhinitis (RR 1.78), and allergic asthma (RR 1.49).
CONCLUSIONS: Despite differences in methodological approaches leading to some variation, the prevalence of NE in the German population can be reasonably estimated at approximately 0.26%. Overlaps and miscoding may have occurred, particularly with other forms of eczema, underscoring the need for reliable diagnostics and standardized coding.