Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) · 2009
[IgE deficiency: a forgotten disease?].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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García Pavón Osorio Susana, López Tiro José Jesús, Gómez Vera Javier
Аннотация
BACKGROUND: Selective IgE deficiency is a profound deficiency (< 5 UI/mL) or absence of serum IgE levels without other immunologic abnormalities. It is usually asymptomatic, but may be associated with recurrent respiratory infections, chronic fatigue, and musculoskeletal complaints.
OBJECTIVE: To describe the evolution and treatment in patients with selective IgE deficiency.
PATIENTS AND METHOD: In selective IgE's deficiency patients identification note, atopy history, concurrent diseases, clinic of allergic diseases, Prick test and prior response to treatment were analyzed.
RESULTS: Eleven patients were included, five women and six men within 16 months to 10 years old. The patients had serum IgE levels < 5 UI with other immunoglobulins and sub-classes in normal levels; except a patient with concomitant IgA and IgE deficiency. The treatment administered was since prophylactic antibiotic to intravenous gammaglobulin.
DISCUSSION: We established the diagnosis of selective IgE deficiency in patient with serum IgE levels < 5 UI/mL associated with recurrent respiratory infections.
CONCLUSIONS: We need more clinic studies to document with precision the selective IgE deficiency.
OBJECTIVE: To describe the evolution and treatment in patients with selective IgE deficiency.
PATIENTS AND METHOD: In selective IgE's deficiency patients identification note, atopy history, concurrent diseases, clinic of allergic diseases, Prick test and prior response to treatment were analyzed.
RESULTS: Eleven patients were included, five women and six men within 16 months to 10 years old. The patients had serum IgE levels < 5 UI with other immunoglobulins and sub-classes in normal levels; except a patient with concomitant IgA and IgE deficiency. The treatment administered was since prophylactic antibiotic to intravenous gammaglobulin.
DISCUSSION: We established the diagnosis of selective IgE deficiency in patient with serum IgE levels < 5 UI/mL associated with recurrent respiratory infections.
CONCLUSIONS: We need more clinic studies to document with precision the selective IgE deficiency.