Neurologia · 2020
Case fatality of COVID-19 in patients with neurodegenerative dementia.
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Reyes-Bueno J A, Mena-Vázquez N, Ojea-Ortega T, Gonzalez-Sotomayor M M, Cabezudo-Garcia P, Ciano-Petersen N L, Pons-Pons G, Castro-Sánchez M V, Serrano-Castro P J
Аннотация
INTRODUCTION: The elderly population is the group most threatened by COVID-19, with the highest mortality rates. This study aims to analyse the case fatality of COVID-19 in a cohort of patients with degenerative dementia.
METHODS: We conducted a descriptive case-control study of a sample of patients diagnosed with primary neurodegenerative dementia.
RESULTS: Twenty-four of the 88 patients with COVID-19 included in the study died: 10/23 (43.4%) patients diagnosed with dementia and 14/65 (21.5%) controls; this difference was statistically significant.
DISCUSSION: Our results suggest that case fatality of COVID-19 is significantly higher among patients with primary degenerative dementia than in other patients with similar mean ages and comorbidities.
METHODS: We conducted a descriptive case-control study of a sample of patients diagnosed with primary neurodegenerative dementia.
RESULTS: Twenty-four of the 88 patients with COVID-19 included in the study died: 10/23 (43.4%) patients diagnosed with dementia and 14/65 (21.5%) controls; this difference was statistically significant.
DISCUSSION: Our results suggest that case fatality of COVID-19 is significantly higher among patients with primary degenerative dementia than in other patients with similar mean ages and comorbidities.
Предметные рубрики MeSH
AgedAged, 80 and overAlzheimer DiseaseBetacoronavirusCOVID-19Cardiovascular DiseasesCase-Control StudiesComorbidityCoronavirus InfectionsDementiaDiabetes MellitusFemaleHumansKidney DiseasesLung DiseasesMaleNeurodegenerative DiseasesPandemicsPneumonia, ViralPrevalenceRisk FactorsSARS-CoV-2SmokingSpain