Subgingival Yeasts Species Amongst Smokers and Nonsmokers With Peri-implantitis.

BACKGROUND

There is a dearth of studies that have assessed yeast species in the subgingival biofilm (SB) samples collected from smokers and nonsmokers with peri-implantitis. This study assesses peri-implant clinical and radiographic profiles and yeasts species in the subgingival SB of cigarette smokers and nonsmokers with peri-implantitis.

METHODS

Participants were divided into 3 groups: group 1, cigarette smokers with peri-implantitis; group 2, nonsmokers with peri-implantitis; and group 3, nonsmokers without peri-implantitis. Information on smoking pack-years and patient demographics was collected. Implant-related parameters were retrieved from health care records. Peri-implant modified plaque and gingival indices (mPI and mGI, respectively), probing depth (PD), and crestal bone loss (CBL) were recorded. The SB samples were collected, subgingival yeasts colonisation was recorded, and yeasts species were identified. P < .05 was considered statistically significant.

RESULTS

Respectively, 22, 22, and 24 individuals were included in groups 1, 2, and 3. In group 1, cigarette smokers had a smoking history of 29.7 ± 7.9 pack-years. The PD, mPI, and mesial and distal CBL were higher in groups 1 (P < .01) and 2 (P < .01) than in group 3. The mGI was higher in group 2 (P < .01) than in groups 1 and 3. The total number of implants in groups 1, 2, and 3 were 22, 22, and 24, respectively. In group 3, implants were in function for a longer duration (12.2 ± 2.3 years; P < .05) than in groups 1 (5.6 ± 1.9 years) and 2 (5.1 ± 0.7 years). Yeasts levels in CFU/mL were higher in group 1 than in groups 2 (P < .05) and 3 (P < .05); they were also higher in group 2 than in group 3 (P < .05). Candida albicans was the most isolated yeasts species, followed by Candida tropicalis, in all groups.

CONCLUSIONS

Cigarette smokers and nonsmokers present similar peri-implant clinicoradiographic profiles, and oral yeasts (predominantly C albicans) seem to play a role in the progression of peri-implant disease in these individuals.