[Personal experience with detection of antibodies against neutrophil cytoplasm].

Detection of antibodies against components of neutrophil cytoplasm (ANCA) is of diagnostic value in Wegener's granulomatosis and in some other types of vasculitis. In the submitted paper the authors discuss methodical aspects of ANCA detection. The most frequently used method for assessment of ANCA is indirect immunofluorescence, at present it is possible to use also the ELISA method. Based on their own group of patients the authors discuss the association of ANCA with various types of diseases and the importance of assessing ANCA during monitoring of immunosuppressive treatment.