The American journal of gastroenterology · 2024
US National Estimates of Contemporary Mortality Rates in Patients With Ulcerative Colitis Undergoing Colectomy.
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Ahmed Newaz Shubidito, Krawchuk Satchel, Buhler Katherine A, Solitano Virginia, Jairath Vipul, Shaheen Abdel Aziz, Seow Cynthia H, Novak Kerri L, Ingram Richard J M, Lu Cathy, Kotze Paulo G, Kaplan Gilaad G, Panaccione Remo, Ma Christopher
Аннотация
INTRODUCTION: Despite a growing armamentarium of medical therapies for ulcerative colitis, colectomy remains an important therapeutic option. To better inform shared decision-making about surgery, we estimated the contemporary risk of mortality after colectomy.
METHODS: Mortality rates were estimated using the National Inpatient Sample (2016-2020). Factors associated with postcolectomy death were evaluated in multivariable regression.
RESULTS: Postcolectomy mortality occurred in 1.2% (95% CI: 0.8%, 1.9%) of hospitalizations. Comorbidity burden, emergent laparotomy, and delays to surgery >5 days after admission were associated with mortality.
DISCUSSION: Colectomy may be associated with mortality; however, this risk is heterogeneous based on patient- and procedural-related factors.
METHODS: Mortality rates were estimated using the National Inpatient Sample (2016-2020). Factors associated with postcolectomy death were evaluated in multivariable regression.
RESULTS: Postcolectomy mortality occurred in 1.2% (95% CI: 0.8%, 1.9%) of hospitalizations. Comorbidity burden, emergent laparotomy, and delays to surgery >5 days after admission were associated with mortality.
DISCUSSION: Colectomy may be associated with mortality; however, this risk is heterogeneous based on patient- and procedural-related factors.