Lymphocytic infiltration in human intracranial tumors--morphologic evidence for a host-immune reaction and comparison with the leukocyte migration inhibition (LMI) test.

Lymphocytic infiltration in and around malignant tumors is generally considered to be an expression of immunologic defence reactions. The extent of such infiltrations correlates with an increase in survival rate. This paper tries to correlate results obtained from leukocyte migration inhibition tests (in vitro) with the presence and the extent of mononuclear infiltrations detected in 67 cases with intracranial tumors of different histologic classification. In the majority of cases there was a close correlation of the results. Possible reasons for discrepant findings are discussed.