Annali italiani di chirurgia · 2016
Sphincter-saving proctectomy for rectal cancer in the elderly.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Ammendola Michele, De Luca Raffaele, Sammarco Giuseppe, Sacco Rosario, Montemurro Severino
Аннотация
AIM: Rectal cancer shows a high incidence in older patients, however, only few reports focused exclusively on rectal cancer with the exclusion of the surgery of the colon. This retrospective study aims to compare short-term and long-term outcomes for rectal cancer in patients more than 75 years old with that observed in younger patients.
MATERIAL OF STUDY: Four hundred consecutive patients operated on for primary rectal adenocarcinoma were collected in a prospective institutional database and divided into two groups: group 1 (≥ 75 years, n =98); group 2 (<75 years, n= 302). Sphincter-saving restaurative proctectomy was the only procedure considered. Main clinical and pathological data, morbidity, clinical anastomotic leakage, reoperation rate, 30-day mortality, overall survival, and cancer-related survival were assessed and compared.
RESULTS: In our experience, advanced age itself is not a contraindication for surgical sphincter-saving proctetomy in rectal cancer patients, although it is associated with higher morbidity and mortality. Overall survival is lower in patients over 75 age, but cancer-related survival is not different between the two groups.
CONCLUSIONS: In our experience, advanced age itself is not a contraindication for surgical sphincter-saving proctetomy in rectal cancer patients, although it is associated with higher morbidity and mortality. Overall survival is lower in patients over 75 age, but cancer-related survival is not different between the two groups.
KEY WORDS: Outcomes, Rectal Cancer, Elderly, Sphincter-saving, Surgery.
MATERIAL OF STUDY: Four hundred consecutive patients operated on for primary rectal adenocarcinoma were collected in a prospective institutional database and divided into two groups: group 1 (≥ 75 years, n =98); group 2 (<75 years, n= 302). Sphincter-saving restaurative proctectomy was the only procedure considered. Main clinical and pathological data, morbidity, clinical anastomotic leakage, reoperation rate, 30-day mortality, overall survival, and cancer-related survival were assessed and compared.
RESULTS: In our experience, advanced age itself is not a contraindication for surgical sphincter-saving proctetomy in rectal cancer patients, although it is associated with higher morbidity and mortality. Overall survival is lower in patients over 75 age, but cancer-related survival is not different between the two groups.
CONCLUSIONS: In our experience, advanced age itself is not a contraindication for surgical sphincter-saving proctetomy in rectal cancer patients, although it is associated with higher morbidity and mortality. Overall survival is lower in patients over 75 age, but cancer-related survival is not different between the two groups.
KEY WORDS: Outcomes, Rectal Cancer, Elderly, Sphincter-saving, Surgery.
Предметные рубрики MeSH
AdenocarcinomaAgedAged, 80 and overAnal CanalAnastomotic LeakChemoradiotherapyCombined Modality TherapyComorbidityDisease-Free SurvivalElective Surgical ProceduresFemaleHumansKaplan-Meier EstimateMaleNeoadjuvant TherapyOrgan Sparing TreatmentsProctocolectomy, RestorativeRectal NeoplasmsRetrospective Studies