Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017
Second re-irradiation for DIPG progression, re-considering "old strategies" with new approaches.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Morales La Madrid Andres, Santa-María Vicente, Cruz Martinez Ofelia, Mora Jaume, Puerta Roldan Patricia, Guillen Quesada Antonio, Suñol Capella Mariona, de Torres Gomez-Pallete Carmen, Lassaletta Alvaro, Laperriere Normand, Villà Salvador, Bouffet Eric
Аннотация
Diffuse intrinsic pontine glioma (DIPG) is an aggressive infiltrative glioma for which no curative therapy is available. Radiation therapy (RT) is the only potentially effective intervention in delaying tumor progression, but only transiently. At progression, re-irradiation is gaining popularity as an effective palliative therapy. However, at second progression, exclusive symptomatic treatment is usually offered. Here we report two patients with DIPG at second progression who were treated with a second re-irradiation course with good response. Importantly, treatment was well tolerated with no irradiation associated acute toxicity identified.