[Incidence of precancerous states an carcinomas of the vulva in young women].

Frequency of precancerous and malignant neoplasms in young (under 45 y.) women in last 20 years has been analysed in the work. There have been analysed VIN and invasive carcinoma progression, localization, coexistence of HPV infection together with intraepithelial neoplasia within uterine cervix and vaginal mucosa. 50% increase of VIN and vulvar cancer, especially in young women during last 10 years has been found. Earlier clinical stadium of vulvar carcinoma is usually found in this group of women compared with older ones. There has been found high percent of multi-focal localization of the vulvar changes in younger patients, especially as far as VIN is concerned. It is often accompanied by HPV infection (60.5%), and rarely by dystrophic changes (20.6%). 11.8% coincidence of cervical intraepithelial neoplasia and vaginal intraepithelial neoplasia, mostly accompanied by HPV, with VIN and vulvar cancer, has also been found.