Clinics and research in hepatology and gastroenterology · 2011
Acute liver failure in children.
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Devictor Denis, Tissieres Pierre, Afanetti Mickael, Debray Dominique
Аннотация
The management of children with acute liver failure mandates a multidisciplinary approach and intense monitoring. In recent years, considerable progress has been made in developing specific and supportive medical measures, but clinical studies have mainly concerned adult patients. There are no specific medical therapies, except for a few metabolic diseases presenting with acute liver failure. Liver transplantation still remains the only definitive therapy in most instances. Recent clinical studies suggest that hepatocyte transplantation may be useful for bridging patients to liver transplantation, for providing metabolic support during liver failure and for replacing liver transplantation in certain metabolic liver diseases.
Предметные рубрики MeSH
ChildCholestasisContraindicationsEnteral NutritionExtracorporeal CirculationGalactosemiasHeart FailureHemochromatosisHemorrhageHepatic EncephalopathyHepatitis, AutoimmuneHepatolenticular DegenerationHumansHypoglycemiaIntracranial HypertensionJaundiceLiver Failure, AcuteLiver Function TestsLiver TransplantationLiver, ArtificialMetabolism, Inborn ErrorsRenal InsufficiencyRespiratory InsufficiencySteroid Metabolism, Inborn ErrorsTyrosinemias