Doklady. Biochemistry and biophysics · 2022
Antitumor Properties of Aqueous Extracts from Inonotus rheades Mycelium and Their Evaluation under Various Cultivation Conditions.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Borovskii G B, Gornostai T G, Polyakova M S, Lozovskaya E A, Nikiforov S B
Аннотация
The antitumor properties of aqueous extracts of Inonotus rheades basidiomycete mushrooms were evaluated when the fungi were cultured on wood discs and wood shavings (birch) at 25 ± 1°C in the dark and under constant illumination with blue light (12.8 W/m2). The aqueous fraction containing water-soluble polysaccharides was isolated and analyzed: WS-5 fraction cultured on wood discs under blue light illumination, WS-8 fraction grown under similar conditions on wood shavings; WS-6 fraction grown in the dark on wood discs; and WS-7 fraction grown under similar conditions on wood shavings. The antitumor effects of the extracts were studied on the model of Ehrlich ascites carcinoma in mice. It was found that the extracts isolated from the basidial fungus Inonotus rheades exhibit antitumor properties and that their accumulation during growth is determined by different cultivation conditions.