Association of ApoE genotype with clinical features and outcome in idiopathic normal pressure hydrocephalus (iNPH): a preliminary report.

Fifteen patients suspected of having iNPH were clinically evaluated and their ApoE genotype determined prior to a possible ventriculoperitoneal shunt insertion. All patients fulfilling our criteria for intervention and who had a shunt implanted with good results were homozygous for the ApoE3/3 genotype.