Clinical imaging · 2017
Preferential sites of metastatic relapse on MRI of initially localized ependymoma in children.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Rootman Mika Shapira, Konen Osnat, Fried Iris, Toledano Helen
Аннотация
OBJECTIVE: Relapse of ependymoma in childhood portends a grave prognosis. While the detection of local recurrence is usually simple, spotting leptomeningeal metastasis might be challenging. We aimed to evaluate possible "hotspots" where metastasis tend to appear.
MATERIALS AND METHODS: Medical records and Magnetic Resonance (MR) studies of all patients diagnosed with brain ependymomas between the years 2000-2015 were reviewed.
RESULTS: Leptomeningeal spread was detected among 42% of relapsed patients. The most common sites were spine and hypothalamic area (26% each).
CONCLUSION: A meticulous assessment of the brain and spine including a thorough evaluation of the hypothalamic area is recommended.
MATERIALS AND METHODS: Medical records and Magnetic Resonance (MR) studies of all patients diagnosed with brain ependymomas between the years 2000-2015 were reviewed.
RESULTS: Leptomeningeal spread was detected among 42% of relapsed patients. The most common sites were spine and hypothalamic area (26% each).
CONCLUSION: A meticulous assessment of the brain and spine including a thorough evaluation of the hypothalamic area is recommended.