Eligibility of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) modulator therapies: cohort of cystic fibrosis registry of Türkiye.
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Akgül Erdal Meltem, Nayır Büyükşahin Halime, Şen Velat, Ayzıt Kılınç Ayşe, Çokuğraş Haluk, Doğan Güzide, Yılmaz Aslı İmran, Ünal Gökçen, Serbes Mahir, Altıntaş Derya Ufuk, Arık Elif, Keskin Özlem, Özaslan Mehmet Mustafa, Karcıoğlu Oğuz, Köse Mehmet, Başaran Abdurrahman Erdem, Çakır Eylül Pınar, Canıtez Yakup, Özdemir Ali, Harmancı Koray, Uytun Salih, Eryılmaz Polat Sanem, Hangül Melih, Yüksel Hasan, Özcan Gizem, Korkmaz Pervin, Kılıç Mehmet, Gayretli Aydın Zeynep Gökçe, Çaltepe Gönül, Can Demet, Doğru Sibel, Kartal Öztürk Gökçen, Süleyman Ayşe, Topal Erdem, Özsezen Beste, Hızal Mina, Demirdöğen Ezgi, Ogun Hamza, Börekçi Şermin, Yazan Hakan, Selimoğlu Şen Hadice, Doğan Demir Ayşegül, Çakır Erkan, Şişmanlar Eyüboğlu Tuğba, Emiralioğlu Nagehan, Pekcan Sevgi, Özçelik Uğur, Doğru Deniz
Аннотация
CASE DESCRIPTION: A 46-year-old woman with a history of breast cancer, anxiety, vitamin D deficiency and gastro-oesophageal reflux disease underwent an EGD, which revealed and led to the removal of duodenal polyps. Six hours post-procedure, she presented with severe abdominal pain radiating to her back, accompanied by nausea. Laboratory results indicated elevated lipase levels, and a computed tomography (CT) scan confirmed acute pancreatitis. The patient was managed with aggressive fluid resuscitation, bowel rest and pain management, leading to an improvement in her condition and subsequent discharge. We believe that the pancreatitis was likely caused by the use of cautery during the endoscopic mucosal resection of duodenal polyps.
CONCLUSION: This case underscores the need for clinicians to recognise acute pancreatitis as a potential complication of EGD, especially in the absence of other common risk factors.
LEARNING POINTS: Acute pancreatitis following oesophagogastroduodenoscopy (EGD) is an uncommon but significant complication.Possible mechanisms include mechanical trauma, gas insufflation or electrical injury during endoscopic mucosal resection.Clinicians should be aware of this potential complication, especially when no typical aetiological factors for pancreatitis are present.