Plastic and reconstructive surgery · 2009
Intracranial volumes in a large series of healthy children.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Kamdar Mehul R, Gomez R Alex, Ascherman Jeffrey A
Аннотация
BACKGROUND: Craniosynostosis alters the normal growth of the infant skull and can influence intracranial pressure and intracranial volume. The purpose of this study was to measure intracranial volumes in a large series of healthy children to serve as a reference for further studies exploring the impact of craniosynostosis and vault remodeling on intracranial growth.
METHODS: A total of 123 children were included in this study from a retrospective review of pediatric emergency room visits for evaluation of head trauma where a head computed tomography scan was performed. Intracranial volumes were obtained using a semiautomated image segmentation technique and volume-rendering software.
RESULTS: Volume measurements were obtained and plotted against age, and a best fit curve approximation was derived. In this study of healthy children, intracranial volume doubled by 9 months of age and tripled by 6 years of age.
CONCLUSIONS: This large study contributes to the existing data demonstrating intracranial volumes in healthy children up to 6 years of age. These data can be used by clinicians as a reference in the assessment of a child presenting with cranial dysmorphology.
METHODS: A total of 123 children were included in this study from a retrospective review of pediatric emergency room visits for evaluation of head trauma where a head computed tomography scan was performed. Intracranial volumes were obtained using a semiautomated image segmentation technique and volume-rendering software.
RESULTS: Volume measurements were obtained and plotted against age, and a best fit curve approximation was derived. In this study of healthy children, intracranial volume doubled by 9 months of age and tripled by 6 years of age.
CONCLUSIONS: This large study contributes to the existing data demonstrating intracranial volumes in healthy children up to 6 years of age. These data can be used by clinicians as a reference in the assessment of a child presenting with cranial dysmorphology.
Предметные рубрики MeSH
Age FactorsBrainCase-Control StudiesCephalometryChildChild, PreschoolCranial SuturesCraniosynostosesFemaleFollow-Up StudiesHumansImaging, Three-DimensionalInfantInfant, NewbornIntracranial PressureMaleOrgan SizeReference ValuesRetrospective StudiesRisk AssessmentSex FactorsTomography, X-Ray Computed